editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. Grape seed extract may be more beneficial for those who are obese. A randomized clinical trial of 30 people found that Pycnogenol (150 mg/day) may help heal vein ulcers from surgery and reduce swelling after 3 months of treatment [25]. For example, Enzogenol is an extract from a pine that grows in California and Mexico (Pinus radiata) that may have cognitive-enhancing effects. Natural Factors Pycnogenol 100mg 30 Veggie Caps. Gotu Kola: Health Benefits, Side Effects, Uses, and More - WebMD Pycnogenol is thought to be an antioxidant that helps protect cells from damage. Pycnogenol has been well-tolerated in most studies performed thus far. . Pycnogenol can help control blood pressure, which helps improve overall heart health. A trial of 39 people with hay fever found that Pycnogenol may reduce nose and eye symptoms. Pycnogenol supplementation reduced skin redness from UV rays in a trial of 21 people over 8 weeks. Note that the numbers in parentheses (1, 2, etc.) (11, 12), While both eliminate pain, the pine bark extract is a far better choice. Pycnogenol is not approved by the FDA for medical use. Pine bark extract is composed of 80% to 85% proanthocyanidins, the monomers catechin and taxifolin (5%), and phenolic acids, including derivatives of benzoic and cinnamic acids (2% to 4%). Pycnogenol: Uses and Risks - WebMD 1 Anti-Aging Beverage, An surprisingstudy found that pine bark extract was far better than aspirin at inhibiting smoking-induced clotting, using lower amounts without the bleeding often found when using aspirin. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. Plus, it reduced total and LDL (bad) cholesterol. What Are the Dangers of Pycnogenol? | Live Healthy - Chron A study of 32 people with heart failure lasting 12 weeks suggests that a combination of Pycnogenol with CoQ10 (PycnoQ10) may improve blood pressure, heart function, edema, and capacity for physical activity [40]. Two studies illustrate the possibilities: One was a randomized, double-blind, placebo-controlled, crossover study in which 26 asthmatic patients were given either a maximum of 200 mg a day of Pycnogenol or placebo for the first period of four weeks and then crossed over to the alternate treatment for the next four weeks. Can Pycnogenol help? Its been noted that taking OPCs and vitamin C supplements at the same time could increase blood pressure if you have hypertension. The antibacterial activity was assessed indicating that the essential oil of pine bark, specifically the proanthocyanidins, were effective against P. aeruginosa, significantly inhibiting its growth. 7. Unlike drug manufacturers, the makers of supplements dont have to show their products are safe or effective before selling them on the market. Protection from inflammation, immunosuppression and carcinogenesis Studies were conducted in Turkey on subjects who underwent abdominal surgery to determine if the pine bark extract could help reduce the inflammation. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. Some small studies suggest it may also protect against coronary artery disease and blood clots. In the placebo group, the retinopathy worsened; whereas, in the Pycnogenol-treated group, there was no deterioration. Additionally, the results showed that the extract has significant anti-pseudomonas activity, making it a potential natural remedy and possible preventive measure for infections. Some people seek to manage ADHD symptoms through an ADHD diet. Lowers Blood Pressure. Rating: 100%. Potential for allergy when taken orally or used on the skin. According to a study in 59 cancer patients, Pycnogenol (150 mg/day) may reduce side effects associated with radiation or chemotherapy, including mouth soreness and ulcers, mouth and eye dryness, nausea, vomiting, diarrhea and weight loss [78]. Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. Research into Pycnogenol has revealed some promising results in over 30 health conditions. But the actual bioavailability of this complex mixture is still unknown. In 19 smokers, increased platelet aggregation was more significantly reduced by 200 mg than either 10 mg or 100 mg of Pycnogenol. It had the best results when combined with compression stockings, but worked just as well alone [28]. Pine bark extract provides many benefits to the skin, including reducing the signs of aging. Pycnogenol Health benefits, dosage, safety, side-effects, and more are clickable links to these studies. Make sure to seek out the advice of your physician prior to using pine bark extract or the branded name, Pycnogenol. Instead, use plain water to wipe yourself and then dry your bottom afterward. Pain score in the Pycnogenol-treated group was reduced by 56%, as compared to 9.6% reduction in the placebo group. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. The crew fell extremely ill from scurvy, an extreme lack of vitamin C. Cartiers crew crossed paths with a Quebec Indian who encouraged them to drink a tea made from pine bark and needles. Due to its anti-inflammatory properties, luteolin is being researched as a potential complementary treatment for multiple . However, in all the above studies insulin levels did not change. Based on another study of 6 trained and 7 untrained people, an antioxidant combination product containing Pycnogenol (Lactaway) may increase endurance. A 2006 study found that children who took a daily pine bark extract supplement for four weeks had significantly lower levels of hyperactivity. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. Some people who have asthma have higher levels of leukotrienes in their blood. Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. The Benefits of DIM - Fort Wayne Physical Medicine Helps Increase Athletic Performance. Organika Pycnogenol 50mg 100 Tablets. from the bark of the French maritime pine tree. Pine bark extract has been studied regarding its relationship to exercise performance, oxidative stress and inflammation to body that has been imposed by exercise. This bark extract has been around for about 450 years. All of our content is written by scientists and people with a strong science background. Seems like it must be pretty amazing, but lets look closer. Pycnogenol Benefits, Dosage & Side Effects - Ayur Times Studies have shown that the tree bark can help decrease common symptoms including hot flashes, mood swings, irregular periods, and others. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. According to research, Pycnogenol may have a multitude of health benefits, which are likely due to this extracts antioxidant and anti-inflammatory properties. (1, 2). In the study, women taking Pycnogenol were more satisfied and compliant to the regimen [24]. In the control group, there were five thrombotic events; whereas the Pycnogenol-treated subjects only experienced nonthrombotic, local flare-ups. (2006). A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. 7 Pine Bark Extract Benefits - LongLifeNutri A Pycnogenol combination product (with l-arginine, alpha lipoic acid, B vitamins, and vitamin K2) may help protect the blood vessels and reduce high homocysteine levels, according to a trial of 25 people [39]. Rakel, D. Integrative Medicine, 3rd edition, Saunders, 2012. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. While pine bark extract is thought to be safe for children, they should only take it for a few weeks at a time. DOI: Chowdhury WK, et al. Pycnogenol lowered leukotrienes as well. Side Effects of Pycnogenol. Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. For most people, pine bark extract doesnt cause any side effects. In addition to general healthy eating, some specific vitamins and minerals may help improve ADHD. A clinical trial of 60 health professionals found that Pycnogenol (150 mg/day) may improve cognitive function, attention, mental performance and specific professional skills after 12 weeks. after four weeks of treatment, Pycnogenol-treated patients showed definite evidence of improved in small blood vessel functions and circulation as compared to those not treated. DOI: Scheff SW, et al. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. A 2017 review reported on the many benefits of using pine bark extract to reduce the effects of aging on skin. Along with the rest of the crew, he developed symptoms of vitamin-C deficiency. In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [54]. According to the National Institutes of Health, its safe for adults to take 50 to 450 milligrams of pine bark extract daily for up to one year. This makes it very hard to set a standard dose. The researchers concluded that pine bark extract may increase production of hyaluronic acid and collagen, which are both found in many popular antiaging products. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. Pycnogenol is the registered trademark brand name of French maritime pine bark extract. In contrast, bleeding still occurred in the control group [61]. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. Pycnogenol can help control blood pressure, which helps improve overall heart health. Consequently, blood pressure is lowered. In the following sections, well discuss the common forms and dosages of Pycnogenol that are commercially available. After stopping Pycnogenol for one month, symptoms Another study found this supplement can even halt progression of vision . Because of its anti-inflammatory effects, nattokinase has been used to help with pain from arthritis, including that of rheumatoid arthritis. Studies have been conducted to review the effects of pine bark extract on pseudomonas infectious wounds. Diabetic retinopathy is a type of eye injury caused by complications from diabetes. They could interact with medicines to suppress the immune system, chemotherapy drugs, and blood thinners. It should never be used as a replacement for approved medical therapies. Improve cardiovascular health. In another study, 61 children with ADHD were given one mg per kg/day of Pycnogenol or placebo over four weeks. Pycnogenol also treatment improved blood vessel function. The results showed that the combination of local and systemic applications of Pycnogenol were the best in terms of ulcer healing even though local application of Pycnogenol also speeded up ulcer healing. PQQ (pyrroloquinoline quinone), also called methoxatin, is a vitamin-like compound that exists naturally in soil and a variety of foods, including spinach, kiwi, soybeans, and human breastmilk . A trial of 132 people found that Pycnogenol (150 mg/day) may improve risk factors of metabolic syndrome including lowering triglyceride levels, blood pressure, and fasting glucose, decreasing waist circumference, and increasing HDL cholesterol levels [29]. In another trial, a combination supplement (Pycnogenol 60 mg/day, L-arginine 690 mg/day and aspartic acid 552 mg/day) improved erectile dysfunction and sexual satisfaction in men after 8 weeks.
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